Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer

Upregulation of fatty acid synthase (FASN), a key enzyme of de novo lipogenesis, is associated with metastasis in colorectal cancer (CRC). However, the mechanisms of regulation are unknown. Since angiogenesis is crucial for metastasis, we investigated the role of FASN in the neovascularization of CR...

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Autori principali: Zaytseva, Yekaterina Y., Elliott, Victoria A., Rychahou, Piotr, Mustain, W.Conan, Kim, Ji Tae, Valentino, Joseph, Gao, Tianyan, O’Connor, Kathleen L., Neltner, Janna M., Lee, Eun Y., Weiss, Heidi L., Evers, B.Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043242/
https://ncbi.nlm.nih.gov/pubmed/24510238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu042
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