Novel siRNA Co-Targeting Strategy as Treatment for Colorectal Cancer

BACKGROUND: RNA interference (RNAi) has the potential to be more selective than small molecule inhibitors and can be used to target proteins, such as RAS, that are currently undruggable. The purpose of our study was to determine the optimal co-targeting strategy of the commonly mutated PI3K/AKT/mTOR...

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Bibliografiske detaljer
Main Authors: Valentino, Joseph D., Elliott, Victoria A., Zaytseva, Yekaterina Y., Rychahou, Piotr G., Mustain, W. Conan, Wang, Chi, Gao, Tianyan, Evers, B. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555567/
https://ncbi.nlm.nih.gov/pubmed/22828149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.05.006
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