Generation of Cancerous Neural Stem Cells Forming Glial Tumor by Oncogenic Stimulation

Neural stem cells in the brain have been shown to be ‘cells of origin’ of certain brain cancers, most notably astrocytomas and medulloblastoma. In particular, in a mouse model, the targeting of genetic modifications for astrocytoma-relevant tumor suppressors to neural stem cells causes malignant ast...

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Detalhes bibliográficos
Main Authors: Lee, Ji-Seon, Lee, Hong Jun, Moon, Bo-Hyun, Song, Seung-Hyun, Lee, Mi-Ok, Shim, Sung Han, Kim, Hyung Seok, Lee, Min Cheol, Kwon, Jeong Taik, Fornace, Albert J., Kim, Seung U., Cha, Hyuk Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043123/
https://ncbi.nlm.nih.gov/pubmed/21755312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-011-9280-4
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