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Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling

Zeta-chain associated protein kinase-70 (Zap70), a Syk family tyrosine kinase, has been reported to be present exclusively in normal T cells, Natural Killer (NK) cells, and B cells, serving as a pivotal regulator of antigen-mediated receptor signaling and development. In this study, we report that Z...

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Detalhes bibliográficos
Main Authors: Cha, Young, Moon, Bo-Hyun, Lee, Mi-Ok, Ahn, Hee-Jin, Lee, Hye-Jin, Lee, Kyung-Ah, Fornace, Albert J., Kim, Kwang-Soo, Cha, Hyuk-Jin, Park, Kyung-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164580/
https://ncbi.nlm.nih.gov/pubmed/20641039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.470
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