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Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells
LIF activates several intracellular signaling pathways including JAK-STAT, PI3K/AKT and MAPK pathways. LIF is an important cytokine for maintenance of pluripotency and self-renewal of mouse ES cells. The JAK-STAT signal plays a key role in maintenance of the pluripotency of ESCs. Recent evidence sho...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670240/ https://ncbi.nlm.nih.gov/pubmed/24058766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.21560 |
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