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Generation of Cancerous Neural Stem Cells Forming Glial Tumor by Oncogenic Stimulation
Neural stem cells in the brain have been shown to be ‘cells of origin’ of certain brain cancers, most notably astrocytomas and medulloblastoma. In particular, in a mouse model, the targeting of genetic modifications for astrocytoma-relevant tumor suppressors to neural stem cells causes malignant ast...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043123/ https://ncbi.nlm.nih.gov/pubmed/21755312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-011-9280-4 |
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