The Role of Glial Mitochondria in α-Synuclein Toxicity

The abnormal accumulation of alpha-synuclein (α-syn) aggregates in neurons and glial cells is widely known to be associated with many neurodegenerative diseases, including Parkinson’s disease (PD), Dementia with Lewy bodies (DLB), and Multiple system atrophy (MSA). Mitochondrial dysfunction in neuro...

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Detalhes bibliográficos
Main Authors: Yu-Mi Jeon, Younghwi Kwon, Myungjin Jo, Shinrye Lee, Seyeon Kim, Hyung-Jun Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-11-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
alpha-synuclein
mitochondrial dysfuncion
neurodegenerative diseases
non-cell autonomous
glia
neuron
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2020.548283/full
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