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RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

The RNA polymerase II largest subunit (Rpb1) contains a unique C-terminal domain (CTD) that plays multiple roles during transcription. The CTD is composed of consensus Y(1)S(2)P(3)T(4)S(5)P(6)S(7) repeats, in which Ser, Thr and Tyr residues can all be phosphorylated. Here we report analysis of CTD T...

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Bibliographische Detailangaben
Hauptverfasser: Hsin, Jing-Ping, Li, Wencheng, Hoque, Mainul, Tian, Bin, Manley, James L
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042873/
https://ncbi.nlm.nih.gov/pubmed/24842995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02112
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