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RNAP II CTD Phosphorylated on Threonine 4 Is Required for Histone mRNA 3′ end Processing

The RNA polymerase II (RNAP II) largest subunit contains a C-terminal domain (CTD) with up to 52 Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) consensus repeats. Serines 2, 5 and 7 are known to be phosphorylated, and these modifications help to orchestrate the interplay between transcription and...

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Detalhes bibliográficos
Main Authors: Hsin, Jing-Ping, Sheth, Amit, Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678764/
https://ncbi.nlm.nih.gov/pubmed/22053051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1206034
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