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Function and Control of RNA Polymerase II C-Terminal Domain Phosphorylation in Vertebrate Transcription and RNA Processing

The C-terminal domain of the RNA polymerase II largest subunit (the Rpb1 CTD) is composed of tandem heptad repeats of the consensus sequence Y(1)S(2)P(3)T(4)S(5)P(6)S(7). We reported previously that Thr 4 is phosphorylated and functions in histone mRNA 3′-end formation in chicken DT40 cells. Here, w...

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Autors principals: Hsin, Jing-Ping, Xiang, Kehui, Manley, James L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054314/
https://ncbi.nlm.nih.gov/pubmed/24752900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00181-14
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