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RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

The RNA polymerase II largest subunit (Rpb1) contains a unique C-terminal domain (CTD) that plays multiple roles during transcription. The CTD is composed of consensus Y(1)S(2)P(3)T(4)S(5)P(6)S(7) repeats, in which Ser, Thr and Tyr residues can all be phosphorylated. Here we report analysis of CTD T...

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Détails bibliographiques
Auteurs principaux: Hsin, Jing-Ping, Li, Wencheng, Hoque, Mainul, Tian, Bin, Manley, James L
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042873/
https://ncbi.nlm.nih.gov/pubmed/24842995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02112
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