Structures and mechanism for the design of highly potent glucocorticoids

The evolution of glucocorticoid drugs was driven by the demand of lowering the unwanted side effects, while keeping the beneficial anti-inflammatory effects. Potency is an important aspect of this evolution as many undesirable side effects are associated with use of high-dose glucocorticoids. The si...

詳細記述

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書誌詳細
主要な著者: He, Yuanzheng, Yi, Wei, Suino-Powell, Kelly, Zhou, X Edward, Tolbert, W David, Tang, Xiaobo, Yang, Jing, Yang, Huaiyu, Shi, Jingjing, Hou, Li, Jiang, Hualiang, Melcher, Karsten, Xu, H Eric
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042175/
https://ncbi.nlm.nih.gov/pubmed/24763108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.52
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