Structures and mechanism for the design of highly potent glucocorticoids

The evolution of glucocorticoid drugs was driven by the demand of lowering the unwanted side effects, while keeping the beneficial anti-inflammatory effects. Potency is an important aspect of this evolution as many undesirable side effects are associated with use of high-dose glucocorticoids. The si...

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Detaylı Bibliyografya
Asıl Yazarlar: He, Yuanzheng, Yi, Wei, Suino-Powell, Kelly, Zhou, X Edward, Tolbert, W David, Tang, Xiaobo, Yang, Jing, Yang, Huaiyu, Shi, Jingjing, Hou, Li, Jiang, Hualiang, Melcher, Karsten, Xu, H Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042175/
https://ncbi.nlm.nih.gov/pubmed/24763108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.52
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