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Structures and mechanism for the design of highly potent glucocorticoids

The evolution of glucocorticoid drugs was driven by the demand of lowering the unwanted side effects, while keeping the beneficial anti-inflammatory effects. Potency is an important aspect of this evolution as many undesirable side effects are associated with use of high-dose glucocorticoids. The si...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: He, Yuanzheng, Yi, Wei, Suino-Powell, Kelly, Zhou, X Edward, Tolbert, W David, Tang, Xiaobo, Yang, Jing, Yang, Huaiyu, Shi, Jingjing, Hou, Li, Jiang, Hualiang, Melcher, Karsten, Xu, H Eric
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042175/
https://ncbi.nlm.nih.gov/pubmed/24763108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.52
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