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Structures and mechanism for the design of highly potent glucocorticoids
The evolution of glucocorticoid drugs was driven by the demand of lowering the unwanted side effects, while keeping the beneficial anti-inflammatory effects. Potency is an important aspect of this evolution as many undesirable side effects are associated with use of high-dose glucocorticoids. The si...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Nature Publishing Group
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042175/ https://ncbi.nlm.nih.gov/pubmed/24763108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.52 |
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