Structures and mechanism for the design of highly potent glucocorticoids

The evolution of glucocorticoid drugs was driven by the demand of lowering the unwanted side effects, while keeping the beneficial anti-inflammatory effects. Potency is an important aspect of this evolution as many undesirable side effects are associated with use of high-dose glucocorticoids. The si...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: He, Yuanzheng, Yi, Wei, Suino-Powell, Kelly, Zhou, X Edward, Tolbert, W David, Tang, Xiaobo, Yang, Jing, Yang, Huaiyu, Shi, Jingjing, Hou, Li, Jiang, Hualiang, Melcher, Karsten, Xu, H Eric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2014
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042175/
https://ncbi.nlm.nih.gov/pubmed/24763108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.52
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