Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism

The intestinal epithelium is subjected to various types of mechanical stress. In this study, we investigated the impact of cyclic stretch on tight junction and adherens junction integrity in Caco-2 cell monolayers. Stretch for 2 h resulted in a dramatic modulation of tight junction protein distribut...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Samak, Geetha, Gangwar, Ruchika, Crosby, Lynn M., Desai, Leena P., Wilhelm, Kristina, Waters, Christopher M., Rao, RadhaKrishna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2014
Gaiak:
Mucosal Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042113/
https://ncbi.nlm.nih.gov/pubmed/24722904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00396.2013
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