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Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53
BACKGROUND: Survivin, a member of the inhibitor of apoptosis (IAP) gene family, has a dual role in mitosis and in apoptosis. It is abundantly expressed in every human tumor, compared with normal tissues. During mitosis Survivin assembles with the chromosomal passenger complex and regulates chromosom...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041913/ https://ncbi.nlm.nih.gov/pubmed/24886358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-107 |
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