RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

Malignant glioma represents the most common primary adult brain tumor in Western industrialized countries. Despite aggressive treatment modalities, the median survival duration for patients with glioblastoma multiforme (GBM), the highest grade malignant glioma, has not improved significantly over pa...

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Библиографические подробности
Главные авторы: Hendruschk, Sandy, Wiedemuth, Ralf, Aigner, Achim, Töpfer, Katrin, Cartellieri, Marc, Martin, Daniel, Kirsch, Matthias, Ikonomidou, Chrysanthy, Schackert, Gabriele, Temme, Achim
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177660/
https://ncbi.nlm.nih.gov/pubmed/21788344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor098
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