RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

Malignant glioma represents the most common primary adult brain tumor in Western industrialized countries. Despite aggressive treatment modalities, the median survival duration for patients with glioblastoma multiforme (GBM), the highest grade malignant glioma, has not improved significantly over pa...

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Detalhes bibliográficos
Main Authors: Hendruschk, Sandy, Wiedemuth, Ralf, Aigner, Achim, Töpfer, Katrin, Cartellieri, Marc, Martin, Daniel, Kirsch, Matthias, Ikonomidou, Chrysanthy, Schackert, Gabriele, Temme, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177660/
https://ncbi.nlm.nih.gov/pubmed/21788344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor098
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