RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

Malignant glioma represents the most common primary adult brain tumor in Western industrialized countries. Despite aggressive treatment modalities, the median survival duration for patients with glioblastoma multiforme (GBM), the highest grade malignant glioma, has not improved significantly over pa...

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Bibliografiske detaljer
Main Authors: Hendruschk, Sandy, Wiedemuth, Ralf, Aigner, Achim, Töpfer, Katrin, Cartellieri, Marc, Martin, Daniel, Kirsch, Matthias, Ikonomidou, Chrysanthy, Schackert, Gabriele, Temme, Achim
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177660/
https://ncbi.nlm.nih.gov/pubmed/21788344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor098
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