RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

Malignant glioma represents the most common primary adult brain tumor in Western industrialized countries. Despite aggressive treatment modalities, the median survival duration for patients with glioblastoma multiforme (GBM), the highest grade malignant glioma, has not improved significantly over pa...

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Dettagli Bibliografici
Autori principali: Hendruschk, Sandy, Wiedemuth, Ralf, Aigner, Achim, Töpfer, Katrin, Cartellieri, Marc, Martin, Daniel, Kirsch, Matthias, Ikonomidou, Chrysanthy, Schackert, Gabriele, Temme, Achim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177660/
https://ncbi.nlm.nih.gov/pubmed/21788344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor098
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