Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53

BACKGROUND: Survivin, a member of the inhibitor of apoptosis (IAP) gene family, has a dual role in mitosis and in apoptosis. It is abundantly expressed in every human tumor, compared with normal tissues. During mitosis Survivin assembles with the chromosomal passenger complex and regulates chromosom...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wiedemuth, Ralf, Klink, Barbara, Töpfer, Katrin, Schröck, Evelin, Schackert, Gabriele, Tatsuka, Masaaki, Temme, Achim
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041913/
https://ncbi.nlm.nih.gov/pubmed/24886358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-107
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky