Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells

BACKGROUND: Survivin, belonging to the inhibitor of apoptosis (IAP) gene family, is abundantly expressed in tumors. It has been hypothesized that Survivin facilitates carcinogenesis by inhibition of apoptosis resulting in improved survival of tumorigenic progeny. Additionally, Survivin plays an esse...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Conde, Marina, Michen, Susanne, Wiedemuth, Ralf, Klink, Barbara, Schröck, Evelin, Schackert, Gabriele, Temme, Achim
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745881/
https://ncbi.nlm.nih.gov/pubmed/29282022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3932-y
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