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Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells
BACKGROUND: Survivin, belonging to the inhibitor of apoptosis (IAP) gene family, is abundantly expressed in tumors. It has been hypothesized that Survivin facilitates carcinogenesis by inhibition of apoptosis resulting in improved survival of tumorigenic progeny. Additionally, Survivin plays an esse...
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| Publicado no: | BMC Cancer |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745881/ https://ncbi.nlm.nih.gov/pubmed/29282022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3932-y |
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