Copper(II)–human amylin complex protects pancreatic cells from amylin toxicity()

Human amylin-derived oligomers and aggregates are believed to play an important role in the pathogenesis of type II diabetes mellitus (T2DM). In addition to amylin-evoked cell attrition, T2DM is often accompanied by elevated serum copper levels. Although previous studies have shown that human amylin...

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Hauptverfasser: Lee, Elizabeth C., Ha, Emmeline, Singh, Sanghamitra, Legesse, Linda, Ahmad, Sana, Karnaukhova, Elena, Donaldson, Robert P., Jeremic, Aleksandar M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041291/
https://ncbi.nlm.nih.gov/pubmed/23793354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cp44542a
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