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Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

The control of mRNA stability plays a central role in orchestrating gene-regulatory networks in hematopoietic cell growth, differentiation and tumorigenesis. HNRNPA0, which encodes an RNA-binding protein shown to regulate transcript stability via binding to the AU-rich elements of mRNAs, is located...

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Hlavní autoři: Young, David J., Stoddart, Angela, Nakitandwe, Joy, Chen, Shann-Ching, Qian, Zhijian, Downing, James R., Le Beau, Michelle M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040907/
https://ncbi.nlm.nih.gov/pubmed/24532040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.098657
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