Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

Uncoupling protein 1 (Ucp1), which is localized in the mitochondrial inner membrane of mammalian brown adipose tissue (BAT), generates heat by uncoupling oxidative phosphorylation. Upon cold exposure or nutritional abundance, sympathetic neurons stimulate BAT to express Ucp1 to induce energy dissipa...

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Dades bibliogràfiques
Autors principals: Ro, Seung-Hyun, Nam, Myeongjin, Jang, Insook, Park, Hwan-Woo, Park, Haeli, Semple, Ian A., Kim, Myungjin, Kim, Jeong Sig, Park, Haewon, Einat, Paz, Damari, Golda, Golikov, Maya, Feinstein, Elena, Lee, Jun Hee
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040599/
https://ncbi.nlm.nih.gov/pubmed/24825887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401787111
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