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Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species
Uncoupling protein 1 (Ucp1), which is localized in the mitochondrial inner membrane of mammalian brown adipose tissue (BAT), generates heat by uncoupling oxidative phosphorylation. Upon cold exposure or nutritional abundance, sympathetic neurons stimulate BAT to express Ucp1 to induce energy dissipa...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040599/ https://ncbi.nlm.nih.gov/pubmed/24825887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401787111 |
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