Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

Uncoupling protein 1 (Ucp1), which is localized in the mitochondrial inner membrane of mammalian brown adipose tissue (BAT), generates heat by uncoupling oxidative phosphorylation. Upon cold exposure or nutritional abundance, sympathetic neurons stimulate BAT to express Ucp1 to induce energy dissipa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ro, Seung-Hyun, Nam, Myeongjin, Jang, Insook, Park, Hwan-Woo, Park, Haeli, Semple, Ian A., Kim, Myungjin, Kim, Jeong Sig, Park, Haewon, Einat, Paz, Damari, Golda, Golikov, Maya, Feinstein, Elena, Lee, Jun Hee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040599/
https://ncbi.nlm.nih.gov/pubmed/24825887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401787111
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