SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

SIRT1 operates as both a tumor suppressor and oncogenic factor depending on the cell context. Whether SIRT1 plays a role in melanoma biology remained poorly elucidated. Here, we demonstrate that SIRT1 is a critical regulator of melanoma cell proliferation. SIRT1 suppression by genetic or pharmacolog...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Ohanna, Mickaël, Bonet, Caroline, Bille, Karine, Allegra, Maryline, Davidson, Irwin, Bahadoran, Philippe, Lacour, Jean-Philippe, Ballotti, Robert, Bertolotto, Corine
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039147/
https://ncbi.nlm.nih.gov/pubmed/24742694
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares