Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype

Here, we showed that the secretome of senescent melanoma cells drives basal melanoma cells towards a mesenchymal phenotype, with characteristic of stems illustrated by increased level of the prototype genes FN1, SNAIL, OCT4 and NANOG. This molecular reprogramming leads to an increase in the low-MITF...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ohanna, Mickaël, Cheli, Yann, Bonet, Caroline, Bonazzi, Vanessa F, Allegra, Marylin, Giuliano, Sandy, Bille, Karine, Bahadoran, Philippe, Giacchero, Damien, Lacour, Jean Philippe, Boyle, Glen M, Hayward, Nicholas F, Bertolotto, Corine, Ballotti, Robert
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2013
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926821/
https://ncbi.nlm.nih.gov/pubmed/24344100
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια