Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response

Vaccinia-related kinase 1 (VRK1) belongs to a group of sixteen kinases associated to a poorer prognosis in human breast carcinomas, particularly in estrogen receptor positive cases based on gene expression arrays. In this work we have studied the potential molecular mechanism by which the VRK1 prote...

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Main Authors: Salzano, Marcella, Vázquez-Cedeira, Marta, Sanz-García, Marta, Valbuena, Alberto, Blanco, Sandra, Fernández, Isabel F., Lazo, Pedro A.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039124/
https://ncbi.nlm.nih.gov/pubmed/24731990
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