The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosphorylate Serine-10 in Histone H3 Required for Transcriptional Activation

Aryl hydrocarbon receptor (AHR) activation by xenobiotic ligands such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is key to their toxicity. Following activation and nuclear translocation, AHR heterodimerizes with the AHR nuclear translocator (ARNT) and binds to AHR response elements (AhREs) in the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kurita, Hisaka, Schnekenburger, Michael, Ovesen, Jerald L., Xia, Ying, Puga, Alvaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Molecular Toxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038787/
https://ncbi.nlm.nih.gov/pubmed/24519526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu027
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge