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Aryl Hydrocarbon Receptor Ligands of Widely Different Toxic Equivalency Factors Induce Similar Histone Marks in Target Gene Chromatin

Posttranslational histone modifications are a critical regulatory mechanism of gene transcription. Previous studies from our laboratory have shown that contingent on binding to its cognate promoter motifs in the Cyp1a1 gene, activation of the aryl hydrocarbon receptor (AHR) by benzo[a]pyrene (BaP) t...

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Detalhes bibliográficos
Main Authors: Ovesen, Jerald L., Schnekenburger, Michael, Puga, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080189/
https://ncbi.nlm.nih.gov/pubmed/21292640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr032
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