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Aryl Hydrocarbon Receptor Nuclear Translocator in Hepatocytes Is Required for Aryl Hydrocarbon Receptor–Mediated Adaptive and Toxic Responses in Liver

The aryl hydrocarbon receptor (AHR) plays a central role in the toxic responses to halogenated dibenzo-p-dioxins (“dioxins”), in the metabolic adaptation to polycyclic aromatic hydrocarbons, and in the development of the mature vascular system. A number of lines of evidence support the idea that the...

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Autori principali: Nukaya, Manabu, Walisser, Jacqueline A., Moran, Susan M., Kennedy, Gregory D., Bradfield, Christopher A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984536/
https://ncbi.nlm.nih.gov/pubmed/20935161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq305
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