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Aryl Hydrocarbon Receptor Ligands of Widely Different Toxic Equivalency Factors Induce Similar Histone Marks in Target Gene Chromatin

Posttranslational histone modifications are a critical regulatory mechanism of gene transcription. Previous studies from our laboratory have shown that contingent on binding to its cognate promoter motifs in the Cyp1a1 gene, activation of the aryl hydrocarbon receptor (AHR) by benzo[a]pyrene (BaP) t...

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Autors principals: Ovesen, Jerald L., Schnekenburger, Michael, Puga, Alvaro
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080189/
https://ncbi.nlm.nih.gov/pubmed/21292640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr032
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