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Oxidants Induce a Corticosteroid-Insensitive Phosphorylation of Histone 3 at Serine 10 in Monocytes

Oxidative stress enhances inflammation and reduces the effectiveness of corticosteroids, but the inflammatory signalling pathways induced by oxidants remain ill-defined. Phosphorylation of histone 3 at serine 10 (H3-Pser10) marks out a subset of inflammatory genes for transcription, several of which...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Marwick, John A., Tudor, Corina, Khorasani, Nadia, Michaeloudes, Charalambos, Bhavsar, Pankaj K., Chung, Kian F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407905/
https://ncbi.nlm.nih.gov/pubmed/25905622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124961
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