AroER Tri-Screen Is a Biologically Relevant Assay for Endocrine Disrupting Chemicals Modulating the Activity of Aromatase and/or the Estrogen Receptor

Endocrine disrupting chemicals (EDCs) interfere with the biosynthesis, metabolism, and functions of steroid hormones, including estrogens and androgens. Aromatase enzyme converts androgen to estrogen. Thus, EDCs against aromatase significantly impact estrogen- and/or androgen-dependent functions, in...

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Detalhes bibliográficos
Main Authors: Chen, Shiuan, Zhou, Dujin, Hsin, Li-Yu, Kanaya, Noriko, Wong, Cynthie, Yip, Richard, Sakamuru, Srilatha, Xia, Menghang, Yuan, Yate-Ching, Witt, Kristine, Teng, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Reproductive and Developmental Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038786/
https://ncbi.nlm.nih.gov/pubmed/24496634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu023
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