AroER Tri-Screen Is a Biologically Relevant Assay for Endocrine Disrupting Chemicals Modulating the Activity of Aromatase and/or the Estrogen Receptor

Endocrine disrupting chemicals (EDCs) interfere with the biosynthesis, metabolism, and functions of steroid hormones, including estrogens and androgens. Aromatase enzyme converts androgen to estrogen. Thus, EDCs against aromatase significantly impact estrogen- and/or androgen-dependent functions, in...

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Main Authors: Chen, Shiuan, Zhou, Dujin, Hsin, Li-Yu, Kanaya, Noriko, Wong, Cynthie, Yip, Richard, Sakamuru, Srilatha, Xia, Menghang, Yuan, Yate-Ching, Witt, Kristine, Teng, Christina
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Reproductive and Developmental Toxicology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038786/
https://ncbi.nlm.nih.gov/pubmed/24496634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu023
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