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AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies

Aromatase inhibitors (AI) are currently the first line therapy for estrogen receptor (ER)-positive postmenopausal women. De novo AI resistance is when a patient intrinsically does not respond to an AI therapy as well as other targeted endocrine therapy. To characterize this type of resistance and to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wong, Cynthie, Wang, Xin, Smith, David, Reddy, Kaladhar, Chen, Shiuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805253/
https://ncbi.nlm.nih.gov/pubmed/22706627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2105-6
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