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The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistance
Estrogen plays important roles in hormone receptor-positive breast cancer. Endocrine therapies, such as the antiestrogen tamoxifen, antagonize the binding of estrogen to estrogen receptor (ER), whereas aromatase inhibitors (AIs) directly inhibit the production of estrogen. Understanding the mechanis...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369003/ https://ncbi.nlm.nih.gov/pubmed/22265958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.12.005 |
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