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The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistance

Estrogen plays important roles in hormone receptor-positive breast cancer. Endocrine therapies, such as the antiestrogen tamoxifen, antagonize the binding of estrogen to estrogen receptor (ER), whereas aromatase inhibitors (AIs) directly inhibit the production of estrogen. Understanding the mechanis...

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書誌詳細
主要な著者: Wong, Cynthie, Chen, Shiuan
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369003/
https://ncbi.nlm.nih.gov/pubmed/22265958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.12.005
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