AroER Tri-Screen Is a Biologically Relevant Assay for Endocrine Disrupting Chemicals Modulating the Activity of Aromatase and/or the Estrogen Receptor

Endocrine disrupting chemicals (EDCs) interfere with the biosynthesis, metabolism, and functions of steroid hormones, including estrogens and androgens. Aromatase enzyme converts androgen to estrogen. Thus, EDCs against aromatase significantly impact estrogen- and/or androgen-dependent functions, in...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Shiuan, Zhou, Dujin, Hsin, Li-Yu, Kanaya, Noriko, Wong, Cynthie, Yip, Richard, Sakamuru, Srilatha, Xia, Menghang, Yuan, Yate-Ching, Witt, Kristine, Teng, Christina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Reproductive and Developmental Toxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038786/
https://ncbi.nlm.nih.gov/pubmed/24496634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu023
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