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N-Benzoyl anthranilic acid derivatives as selective inhibitors of aldo–keto reductase AKR1C3

Human aldo–keto reductases AKR1C1–AKR1C3 are involved in the biosynthesis and inactivation of steroid hormones and prostaglandins and thus represent attractive targets for the development of new drugs. We synthesized a series of N-benzoyl anthranilic acid derivatives and tested their inhibitory acti...

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Detaylı Bibliyografya
Asıl Yazarlar: Sinreih, Maša, Sosič, Izidor, Beranič, Nataša, Turk, Samo, Adeniji, Adegoke O., Penning, Trevor M., Rižner, Tea Lanišnik, Gobec, Stanislav
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038446/
https://ncbi.nlm.nih.gov/pubmed/22897946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.07.062
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