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Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase
DNA damage repair is essential for the maintenance of genetic integrity in all organisms. Unrepaired or imprecisely repaired DNA can lead to mutagenesis, cell death or malignant transformation. DNA damage in the form of double-strand breaks (DSBs) can occur as a result of both exogenous insults, suc...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2006
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036680/ https://ncbi.nlm.nih.gov/pubmed/16793422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(05)09031-2 |
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