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Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase

DNA damage repair is essential for the maintenance of genetic integrity in all organisms. Unrepaired or imprecisely repaired DNA can lead to mutagenesis, cell death or malignant transformation. DNA damage in the form of double-strand breaks (DSBs) can occur as a result of both exogenous insults, suc...

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Xehetasun bibliografikoak
Egile Nagusiak: Weinstock, David M., Nakanishi, Koji, Helgadottir, Hildur R., Jasin, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036680/
https://ncbi.nlm.nih.gov/pubmed/16793422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(05)09031-2
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