Physiological IgM Class Catalytic Antibodies Selective for Transthyretin Amyloid

Peptide bond-hydrolyzing catalytic antibodies (catabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence for beneficial catabodies. Transthyretin (TTR) forms misfolded β-sheet aggregates responsible for age-associated amyloidosis. We describe nucleophilic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Planque, Stephanie A., Nishiyama, Yasuhiro, Hara, Mariko, Sonoda, Sari, Murphy, Sarah K., Watanabe, Kenji, Mitsuda, Yukie, Brown, Eric L., Massey, Richard J., Primmer, Stanley R., O'Nuallain, Brian, Paul, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036335/
https://ncbi.nlm.nih.gov/pubmed/24648510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557231
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados