Physiological IgM Class Catalytic Antibodies Selective for Transthyretin Amyloid

Peptide bond-hydrolyzing catalytic antibodies (catabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence for beneficial catabodies. Transthyretin (TTR) forms misfolded β-sheet aggregates responsible for age-associated amyloidosis. We describe nucleophilic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Planque, Stephanie A., Nishiyama, Yasuhiro, Hara, Mariko, Sonoda, Sari, Murphy, Sarah K., Watanabe, Kenji, Mitsuda, Yukie, Brown, Eric L., Massey, Richard J., Primmer, Stanley R., O'Nuallain, Brian, Paul, Sudhir
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036335/
https://ncbi.nlm.nih.gov/pubmed/24648510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557231
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi