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Beneficial Catalytic Immunity to Aβ Peptide

We review attempts to treat Alzheimer disease with antibodies that bind amyloid β peptide (Aβ) and the feasibility of developing catalytic antibodies for this purpose. Naturally occurring immunoglobulin M (IgM) class antibodies that hydrolyze Aβ and inhibit Aβ aggregation were identified. The produc...

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Detalhes bibliográficos
Main Authors: Paul, Sudhir, Planque, Stephanie, Nishiyama, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946056/
https://ncbi.nlm.nih.gov/pubmed/20370602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2009.0958
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