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Beneficial Catalytic Immunity to Aβ Peptide
We review attempts to treat Alzheimer disease with antibodies that bind amyloid β peptide (Aβ) and the feasibility of developing catalytic antibodies for this purpose. Naturally occurring immunoglobulin M (IgM) class antibodies that hydrolyze Aβ and inhibit Aβ aggregation were identified. The produc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946056/ https://ncbi.nlm.nih.gov/pubmed/20370602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2009.0958 |
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