Essential Roles of Neutral Ceramidase and Sphingosine in Mitochondrial Dysfunction Due to Traumatic Brain Injury

In addition to immediate brain damage, traumatic brain injury (TBI) initiates a cascade of pathophysiological events producing secondary injury. The biochemical and cellular mechanisms that comprise secondary injury are not entirely understood. Herein, we report a substantial deregulation of cerebra...

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Autores principales: Novgorodov, Sergei A., Riley, Christopher L., Yu, Jin, Borg, Keith T., Hannun, Yusuf A., Proia, Richard L., Kindy, Mark S., Gudz, Tatyana I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036326/
https://ncbi.nlm.nih.gov/pubmed/24659784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530311
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