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Neutral Ceramidase: advances in mechanisms, cell regulation, and roles in cancer

Extensive research conducted in the last three decades has identified the roles for the main bioactive sphingolipids, namely ceramide, sphingosine, and sphingosine 1-phosphate (S1P) as key regulators of cellular homeostasis, growth and death. One of the major groups of enzymes in the ceramide pathwa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Adv Biol Regul
Hauptverfasser: Coant, Nicolas, Hannun, Yusuf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347532/
https://ncbi.nlm.nih.gov/pubmed/30389354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2018.10.005
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