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Neutral Ceramidase: advances in mechanisms, cell regulation, and roles in cancer

Extensive research conducted in the last three decades has identified the roles for the main bioactive sphingolipids, namely ceramide, sphingosine, and sphingosine 1-phosphate (S1P) as key regulators of cellular homeostasis, growth and death. One of the major groups of enzymes in the ceramide pathwa...

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Bibliographic Details
Published in:Adv Biol Regul
Main Authors: Coant, Nicolas, Hannun, Yusuf A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347532/
https://ncbi.nlm.nih.gov/pubmed/30389354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2018.10.005
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