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AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells

Despite advances in the field, colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Research into bioactive sphingolipids over the past two decades has played an important role in increasing our understanding of the pathogenesis and therapeutics of CRC. In the compl...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Coant, Nicolas, García-Barros, Mónica, Zhang, Qifeng, Obeid, Lina M., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041258/
https://ncbi.nlm.nih.gov/pubmed/29662189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0236-x
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