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Roles of SLX1–SLX4, MUS81–EME1, and GEN1 in avoiding genome instability and mitotic catastrophe

The resolution of recombination intermediates containing Holliday junctions (HJs) is critical for genome maintenance and proper chromosome segregation. Three pathways for HJ processing exist in human cells and involve the following enzymes/complexes: BLM–TopoIIIα–RMI1–RMI2 (BTR complex), SLX1–SLX4–M...

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Dades bibliogràfiques
Autors principals: Sarbajna, Shriparna, Davies, Derek, West, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035540/
https://ncbi.nlm.nih.gov/pubmed/24831703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.238303.114
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