Ca(2+)-Activated K(+) Channel–3.1 Blocker TRAM-34 Attenuates Airway Remodeling and Eosinophilia in a Murine Asthma Model

Key features of asthma include bronchial hyperresponsiveness (BHR), eosinophilic airway inflammation, and bronchial remodeling, characterized by subepithelial collagen deposition, airway fibrosis, and increased bronchial smooth muscle (BSM) mass. The calcium-activated K(+) channel K(Ca)3.1 is expres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Girodet, Pierre-Olivier, Ozier, Annaig, Carvalho, Gabrielle, Ilina, Olga, Ousova, Olga, Gadeau, Alain-Pierre, Begueret, Hugues, Wulff, Heike, Marthan, Roger, Bradding, Peter, Berger, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2013
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035224/
https://ncbi.nlm.nih.gov/pubmed/23204391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0103OC
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